UHPLC Column, RP C4 Butyl, 1.8um, 100A. 2.1mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4 Butyl is a reversed-phase HPLC and UHPLC stationary phase designed for the separation of hydrophobic to moderately hydrophobic compounds. Manufactured using a traditional butyl (C4) bonded phase on ultra-high purity silica and fully double end capped, it provides reproducible retention, excellent peak shape, and reduced secondary interactions. The shorter alkyl chain offers less retention than C8 or C18 phases, making it well suited for fast analyses, biomolecules, peptides, proteins, and method development where excessive retention is undesirable.
68104-05P-2 is a UHPLC column packed with 1.8 µm RP C4 Butyl particles featuring a 100 Å pore size in a 2.1 mm ID x 50 mm format. The short 50 mm length is optimized for high-speed separations, while the 1.8 µm particle technology provides exceptional efficiency, increased peak capacity, and superior chromatographic performance compared to larger particle columns. This column is specifically engineered for high-pressure UHPLC applications and is intended to take full advantage of UHPLC instrumentation capable of operating at the elevated pressures generated by sub-2 µm particles. Typical operating flow rates are approximately 0.2–0.4 mL/min. Because of the low flow rates required, standard HPLC systems must be capable of delivering consistent and accurate low-flow performance if used with this column.
Ideal for very hydrophobic and neutral compounds, this column offers rapid analysis times, reduced solvent consumption, increased laboratory throughput, and excellent performance for method development. While compatible HPLC systems may be used in some applications, the column is designed primarily for UHPLC operation where its full efficiency, speed, and resolution benefits can be realized.
Key Benefits
RP C4 Butyl stationary phase
Fully double end capped
Traditional butyl bonded phase
Ultra-high purity silica support
Engineered for UHPLC applications
1.8 µm particle technology
Exceptional column efficiency
Increased peak capacity
Fast analysis times
Reduced solvent consumption
Typical Applications
UHPLC analysis
High-speed separations
Method development
Peptide analysis
Protein analysis
Hydrophobic compound analysis
Neutral compound analysis
Pharmaceutical analysis
Bioanalytical applications
High-throughput laboratories
Specifications
Product Type: UHPLC Column
Stationary Phase: RP C4 Butyl
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double End Capped
Particle Size: 1.8 µm
Pore Size: 100 Å
Column Dimensions: 2.1 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 0.2–0.4 mL/min
Brand: Cogent
Important Notes
Specifically designed for UHPLC operation and high-pressure reversed-phase separations
Delivers maximum performance when used on a UHPLC system designed for sub-2 µm particle columns
May be used on compatible HPLC systems that can reliably operate at the required pressures and low flow rates
Sub-2 µm particles generate significantly higher backpressure than conventional HPLC columns
The 2.1 mm ID format reduces solvent consumption and is well suited for LC-MS applications
Standard HPLC systems must be capable of precise and reproducible operation at approximately 0.2–0.4 mL/min
Samples should be filtered through a 0.2 µm syringe filter prior to injection
Short column length provides rapid analysis and increased sample throughput
Lower retention than comparable C8 or C18 stationary phases